An experimental study of pulsed micro-flows pertinent to continuous subcutaneous insulin infusion therapy
نویسندگان
چکیده
An experimental study was conducted to investigate the unsteady micro-flow driven by an insulin pump commonly used in continuous subcutaneous insulin infusion (CSII) therapy. A microscopic particle image velocimetry (PIV) system was used to characterize the transient behavior of the micro-flow upon the pulsed excitation of the insulin pump in order to elucidate the underlying physics for a better understanding of the microphysical process associated with the insulin delivery in CSII therapy. The effects of air bubbles entrained inside the microsized CSII tubing system on the insulin delivery process were also assessed based on the micro-PIV measurements. While most solutions to insulin occlusion-related problems are currently based on clinical trials, the findings derived from the present study can be used to provide a better guidance for the troubleshooting of insulin occlusion in CSII therapy.
منابع مشابه
An Experimental Study of Pulsed Micro-Flows Driven by an Insulin Pump
In recent years, there is a surge in the popularity of using insulin pump or continuous subcutaneous insulin infusion (CSII) therapy, as opposed to multiple daily injections (MDI) by insulin syringe or an insulin pen. Some case studies have suggested that insulin delivery failure may be caused by the precipitation of insulin within the infusion set. Speculation also exists that the flow of insu...
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